Major Depressive Disorder
To be diagnosed with major depressive disorder, a patient must exhibit a depressed mood or loss of interest in most daily activities, plus at least five of nine major symptoms during a two week period. Major symptoms include significant weight gain or loss; insomnia or hypersomnia; psychomotor agitation or retardation; fatigue or loss of energy; feelings of guilt or worthlessness; indecisiveness or impaired ability to concentrate; and recurrent thoughts of death or suicide.
